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Biobattalion Webinar Series Chapter 2 – Dr. Adarsh Dharan

Dr. Adarsh Dharan, Research Associate Professor, Loyola University Chicago, USA delivered an exciting talk titled; ‘Understanding HIV- 1 Nuclear Import’. He discussed the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection and several other factors associated with their entries into the nucleus by showing these nuclear import kinetics during infection in a number of cell lines.

He further explained that, unlike other previous studies, reverse transcription is not a process that is completed in the cytoplasm but still an ongoing process once the nuclear import is even done. He presented his study confirming the presence of assembled capsids inside the nucleus and also the functional role of these capsids there.

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