What’s in our cells?
Have you ever wondered what makes up the cells of your body? Watch this video to find out about some of the basic components of our cells.
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Have you ever wondered what makes up the cells of your body? Watch this video to find out about some of the basic components of our cells.
Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA is methylated and whether 5mC has a regulatory role in this context. Here, we used bisulfite-independent single-molecule sequencing of native human and mouse DNA to study mitochondrial 5mC across different biological conditions.
Men and Women suffer differently from infections with the SARS-CoV-2 virus. In this video, we will look at the biological reasons for the gender differences of the Covid19 disease by better understanding how this virus works and how different our bodies are.
DNA is known as the molecule that carries the instructions necessary for cell functioning and genetic inheritance. Recently, we discovered a new function for extracellular DNA: pathogen control. After fragmenting DNA into smaller molecules, they can inhibit specific species from a range of organisms. This video explains the background of the “No-self” treatment and how this treatment could help us in the fight against antimicrobial resistance.
To survive in the environment, bacteria sometimes need to kill other bacteria to get all the food and space. In this video, you will learn about a bow-and-arrow nanoweapon that bacteria use to shoot deadly arrows into other bacteria. Hopefully, one day we can use this weapon in the fight against antimicrobial resistance.
The structural flexibility of RNA underlies fundamental biological processes, but there were no methods to explore the multiple conformations adopted by RNAs in vivo. We developed cross-linking of matched RNAs and deep sequencing (COMRADES) for in-depth RNA conformation capture, and a pipeline for the retrieval of RNA structural ensembles.
Using COMRADES, we determined the architecture of the Zika virus RNA genome inside cells and identified multiple site-specific interactions with human noncoding RNAs.
The zika virus genome is a single-stranded RNA molecule. Not much was known about its structure. A collaborative initiative between two Universities in the United Kingdom solved this riddle and developed a method to explore multiple conformations adopted by RNAs in vivo in virus-infected cells. Just like a person can fold their body into multiple yoga positions, the Zika virus genome can do similar. Watch this video to learn how!
What has a virus in common with a kinder surprise egg? Surprisingly, a lot! Watch this video to learn how scientists can look into viruses and study their insides. In this video, you will learn about virions, capsids, and genomes. You might also get hungry!
Explaining Kids About Cancer
